Postdoc ‘AI/Computational biology for Cancer Research on Uveal Melanoma’

The Medical Oncology department at the Radboudumc and the Data Science group at the Radboud University Is looking for a Postdoc ‘AI/computational biology for cancer research on uveal melanoma’.

The aim of our project is to improve our mechanistic understanding of the immunological processes critical for response or underlying resistance to immunotherapy, to guide hypothesis-driven small clinical trials in the future.

Uveal melanoma is a rare, highly aggressive cancer originating from melanocytes in the eye. There are no standard treatment options available for uveal melanoma. In particular, novel immunotherapy treatments that are effective in other types of cancer, including cutaneous (skin) melanoma, seem to work less well in uveal melanoma. This lack of response might be due to the immune-privileged status of the eye: immune cells are usually not able to enter the eye.

Therefore, in this project, funded by a grant from the Hanarth foundation, we will study the immune landscape of uveal melanoma using multiple types and sources of data. The use of heterogeneous, observational datasets is unavoidable when studying rare cancers, but comes with a high risk of confounding and selection biases.

Duration: 3 years

Tasks

For this Postdoc in ‘AI/Computational biology for Cancer Research on Uveal Melanoma’ the candidate will:

  • Develop and apply methods for generating simulated data to develop and optimize data analysis protocols.
  • Improve our custom deep learning pipeline for processing imaging data.
  • Develop and apply data fusion techniques to available, heterogeneous datasets.
  • Actively participate in multidisciplinary scientific meetings.

Salary

  • A minimum of € 2986 – maximum of € 4707 gross per month
  • Radboud university medical center provides annual courses, both professional and personal.
  • In addition to the monthly salary and an annual vacation allowance of 8%, the candidate will receive an end-of-year bonus of 8.3%.
  • Radboud university medical center pays 70% of the pension premium. While candidates pay the rest of the premium with their gross salary.
  • Discount on health insurance as well
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Job Requirements

The Postdoc position in ‘AI/Computational biology for Cancer Research on Uveal Melanoma’ seek candidates with

  • A PhD degree and excellent track record in a relevant field (including, but not limited to, computational biology, AI, data science, molecular biology, immunology, oncology, bioinformatics, statistics, computer science, physics, or mathematics). 
  • Strong analytical skills.
  • Experience in or willingness to learn programming, with proficiency in data science-oriented languages such as R and python considered a plus.
  • Experience in or willingness to learn modeling and/or simulation methodologies, such as differential equations, agent-based models, or generative machine learning models.
  • Able to work both independently and in a team.
  • A strong interest in translational research.
  • Interpersonal and communication skills to effectively collaborate and communicate in an interdisciplinary research setting.
  • A high level of proficiency in English.

Application Process

For application to the Postdoc ‘AI/Computational biology for Cancer Research on Uveal Melanoma’, attach the following:

  • curriculum vitae and
  • cover letter

To apply, click here

Application Deadline: July 01, 2022.

For more information on Postdoc ‘AI/Computational biology for Cancer Research on Uveal Melanoma’, visit the official site.

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